Nephrol Dial Transplant (2000) 15: 2053-2056
© 2000 European Renal Association-European Dialysis and Transplant Association
Teaching Points
Non-diabetic nodular glomerulosclerosis recurring in a renal graft
(Section Editor: K. Kühn)
1 Departments of Internal Medicine and 2 Pathology, University of Tartu, 3 Dialysis Unit, Pelgulinna Hospital, 4 Pathology Division, Mustamäe Hospital, Tallinn, Estonia, and 5 Nephrology Division, University of Heidelberg, Germany light-chain deposition disease; nodular glomerulosclerosis; proteinuria; renal biopsy
Keywords: light-chain deposition disease; nodular glomerulosclerosis; proteinuria; renal biopsy
Introduction
Nodular glomerulosclerosis is usually considered the hallmark of diabetic nephropathy. Similar morphology may also be seen, however, in some relatively rare non-diabetic conditions. The following case gives unique information on the natural history of one of these conditions, i.e. light-chain deposition disease.
Case
A 38-year-old female patient was admitted for further evaluation. She had a 6 months' history proteinuria, pretibial oedema, and normochromic anaemia. There was no history of renal disease and serum creatinine concentration was in the normal range. She complained of chronic fatigue and decreased appetite. She was noted to have moderated
Comment
Discussion
Differential diagnosis
Serodiagnostics
Teaching Point
Acknowledgments
Notes
References