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Nephrol Dial Transplant (2000) 15: 1696-1699
© 2000 European Renal Association-European Dialysis and Transplant Association

Teaching Points

Nephrotic syndrome after renal percutaneous transluminal angioplasty

(Section Editor: K. Kühn)

Jaume Almirall, Inmaculada Mendez1, Ricard Comet and Xavier Andreu1

Nephrology Unit and 1 Pathology Service, Corporació Sanitaria Parc Taulí, Sabadell, Spain

Keywords: renovascular hypertension; percutaneous angioplasty; nephrotic syndrome

Introduction

Several anecdotal case reports have described an association between renal artery stenosis and the nephrotic syndrome [1–4]. The aetiology of this nephrotic state has been related to the hyperrreninaemia secondary to renal artery stenosis [2–4]. This mechanism has been supported by the evidence showing occurrence of proteinuria in experimental animals infused with renin or angiotensin II [5,6]. Resolution of proteinuria has been observed after nephrectomy [2,4,7–11], reconstruction of the affected renal artery [12–15] or administration of angiotensin-converting enzyme inhibitor [7,16–21].

We observed a case of renovascular hypertension with bilateral renal artery stenosis who presented a sudden nephrotic syndrome following a transluminal angioplasty of the functioning kidney. This observation suggests that in addition to hormonal factors, the intrarrenal haemodynamics must be . . . [Full Text of this Article]

Case report

Discussion

Teaching Point

Notes

References


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