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Nephrol Dial Transplant (2000) 15: 1679-1683
© 2000 European Renal Association-European Dialysis and Transplant Association

Case Reports

Fibrillary/immunotactoid glomerulonephritis in HIV-positive patients: a report of three cases

Mark Haas1,, Srinivasan Rajaraman2, Tejinder Ahuja3, Martin Kittaka4 and Tito Cavallo5

1 Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 2 Department of Pathology, Section of Renal Immunopathology, University of Texas Medical Branch, Galveston, TX, 3 Division of Nephrology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 4 Department of Medicine, Elmhurst Memorial Hospital, Elmhurst, IL and 5 Department of Pathology, University of Cincinnati College of Medicine, Cincinnati, OH, USA

Keywords: acquired immune deficiency syndrome; fibrillary glomerulonephritis; hepatitis C; HIV; immunotactoid glomerulopathy; nephrotic syndrome



   Introduction
 
Renal disease is a common complication in patients infected with human immunodeficiency virus (HIV) [1]. Among HIV-positive patients undergoing a renal biopsy, the most common lesion observed is HIV-associated nephropathy (HIVAN). This histologically resembles the collapsing glomerulopathy variant of focal-segmental glomerulosclerosis, and typically presents with nephrotic range proteinuria and renal insufficiency with rapid progression to end-stage renal disease in the majority of cases [1]. Like idiopathic collapsing glomerulopathy [2], HIVAN shows a strong predilection for affecting black patients, both among intravenous drug abusers (IVDA) and non-IVDA [1]. In a review of over 200 patients from multiple centres with HIVAN, 89% were black [3]. By contrast, HIVAN accounted for fewer than 10% of renal biopsy diagnoses in HIV-infected white patients in two European studies [4,5]. In these latter patient populations, immune complex-related glomerulopathies comprised the majority of . . . [Full Text of this Article]



   Cases
 
Patient 1
Patient 2
Patient 3


   Discussion
 


   Notes
 


   References
 

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