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Nephrol Dial Transplant (2000) 15: 1677-1678
© 2000 European Renal Association-European Dialysis and Transplant Association

Technical Note

Mnemotechnical note on the use of Cockcroft creatinine clearance formula for the validation of a 24-h urine collection

Albert Fournier,1 and Jean Michel Achard2

1 Service de Néphrologie, CHU Amiens, 2 Laboratoire de Physiologie, CHU Limoges, France

Introduction

The Cockcroft and Gault formula [1] for estimation of creatinine clearance (CCr) is well known by clinicians and universally used to estimate renal function reliably without the pitfalls of 24-h urine collection. Its use for estimation of 24-h creatininuria (namely when serum creatinine (SCr) is not available), is, however, unusual and subject to errors. The primary misunderstanding is the incorrect assumption that the numerator of the equation represents 24-h creatininuria when it actually represents only the creatininuria of 1000 min when SCr is expressed per litre and of only 100 min when SCr is expressed per decilitre. To . . . [Full Text of this Article]

Why does the numerator of the Cockroft creatinine clearance formula represent the creatininuria of 1000 min?

Validation of a 24-h urine collection

Conclusion

Notes

References


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