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Nephrol Dial Transplant (2000) 15: 1509-1511
© 2000 European Renal Association-European Dialysis and Transplant Association

Editorial Comments

Smoking and the kidney

Stephan R. Orth, Hiroaki Ogata and Eberhard Ritz

Keywords: smoking; progression; proteinuria; sympathetic activation; nitric oxide; diabetic nephropathy

Introduction

Amongst the health hazards of smoking carcinogenesis [1], cardiovascular disease [1,2] and lung disease [1,3] have attracted considerable attention. In contrast, until recently the potential impact of smoking on renal function and renal disease have remained largely unnoticed [4]. Admittedly, the number of patients with smoking-related renal problems is considerably smaller than the number of patients with malignancy, cardiovascular or pulmonary problems, but in view of the high cost of renal replacement therapy the problem is by no means trivial. Certainly the consequences for the health budget are quite considerable [4].

There is no doubt that smoking promotes atherogenesis in various vessels including the abdominal aorta [5] and, by implication, plays a prominent role in the genesis of atherosclerotic renal artery stenosis and ischaemic nephropathy [6–8]. There is also convincing . . . [Full Text of this Article]

The acute effects of smoking on the kidney

The chronic effects of smoking on the kidney

The effects of smoking on development and progression of diabetic nephropathy

The effects of smoking on progression in patients with non-diabetic renal disease

Conclusion

Acknowledgments

Notes

References


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