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Nephrol Dial Transplant (2000) 15: 102-103
© 2000 European Renal Association-European Dialysis and Transplant Association

Case Reports

Association of Bartter's syndrome with vasculitis

Boriana Deliyska1, Valentin Lazarov1, Violina Minkova2, Dobrin Nikolov1 and Ivan Tishkov1

1 Clinical Center of Nephrology and 2 Department of Pathology, Medical University, Sofia, Bulgaria

Correspondence and offprint requests to: Dr B. Deliyska, Clinical Center of Nephrology, Medical University, Damian Gruer Str. 8, Sofia 1303, Bulgaria.

Keywords: alkalosis; Bartter's syndrome; Gitelman syndrome; hypokalaemia; vasculitis; immunosuppressive therapy



   Introduction
 
Bartter's syndrome is a rare disorder manifested by primary inherited renal tubular hypokalaemic metabolic alkalosis, marked elevation in plasma renin and aldosterone activity, pressor insensitivity to angiotensin II and normal or low values of plasma sodium, plasma chloride, low blood pressure and hyperplasia of the juxtaglomerular apparatus [1]. It is now evident that this syndrome does not represent a unique entity but encompasses a variety of disorders of renal electrolyte transport [2]. A case of Bartter's syndrome with severe hypokalaemic alkalosis, hyperaldosteronism and hyperreninaemia with low blood pressure, associated with ANCA-negative vasculitis and minor glomerular changes is discussed. After therapy with steroids, plasmapheresis and cyclophosphamide, potassium supplements and Aldactone . . . [Full Text of this Article]



   Case
 
Clinical evolution


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