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Nephrol Dial Transplant (1999) 14: 2201-2203
© 1999 European Renal Association-European Dialysis and Transplant Association

Case Reports

Severe hypokalaemia and respiratory arrest due to renal tubular acidosis in a patient with Sjögren syndrome

Hiroshi Ohtani, Hirokazu Imai, Takahito Kodama, Keiko Hamai, Atsushi Komatsuda, Hideki Wakui and Akira B. Miura

Third Department of Internal Medicine, Akita University School of Medicine, Akita, Japan

Correspondence and offprint requests to: Hiroshi Ohtani, MD, Third Department of Internal Medicine, Akita University School of Medicine, 1-1-1, Hondo, Akita 010, Japan.

Keywords: hypokalamia; Sjögren syndrome; renal tubular acidosis; respiratory arrest; tubulo-interstitial nephritis



   Introduction
 
Tubulo-interstitial nephritis and/or renal tubular acidosis occur in almost 25–40% of patients with Sjögren syndrome, characterized by the presence of kerato-conjunctivitis, xerostomia and chronic inflammatory sialoadenitis [1,2]. Paralysis of the extremities is well known to be a complication of hypokalaemia due to renal tubular acidosis. A prolonged state of severe hypokalaemia may cause muscle weakness to progress occasionally into respiratory arrest due to paralysis of the respiratory muscle. We present a case of respiratory arrest due to severe hypokalaemia in a patient with Sjögren syndrome.



   Case
 
A 56-year-old woman was transferred to Akita University Hospital by ambulance because of respiratory arrest on February 12, 1998. One month before admission, she consulted a local hospital complaining of general fatigue and weakness of the limbs. . . . [Full Text of this Article]



   Discussion
 


   References
 

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