Nephrology Dialysis Transplantation, Vol 12, Issue 12 2588-2591, Copyright © 1997 by Oxford University Press
S Mak, E Gwi, K Chan, N Wong, K Lo, K Lee and A Wong
Background: Several studies had suggested that
non-diabetic renal disease (NDRD) was common among non-insulin dependent
diabetes mellitus (NIDDM) patients with renal involvement.
Methods: We prospectively studied the prevalence of
NDRD among a Chinese NIDDM population. Renal biopsy specimens were
evaluated with light-, immunohistological and electron-microscopy. The
cohort consisted of 51 patients who had NIDDM and proteinuria >1
g/24 h. Results: Patients with both isolated diabetic
nephropathy (DN, n=34) and NDRD (n=17) had comparable duration of DM,
creatinine clearance, serum creatinine, albumin and glycosylated
haemoglobin levels, as well as incidences of retinopathy, neuropathy and
hypertension. Significantly more patients with NDRD had microscopic
haematuria (P=0.043) or non-nephrotic proteinuria (P=0.004). IgA
nephropathy accounted for 59% of the NDRD identified.
Conclusions: In this study, microscopic haematuria and
non-nephrotic proteinuria predicted the presence of NDRD among NIDDM
patients presenting with renal disease. Key words:
microscopic haematuria; non-diabetic renal disease; non-insulin dependent
diabetes mellitus; non-nephrotic proteinuria
ORIGINAL ARTICLES
Clinical predictors of non-diabetic renal disease in patients with non-insulin dependent diabetes mellitus
Renal Unit, Department of Medicine and Department of Pathology, Kwong Wah Hospital, Waterloo Road, Kowloon, Hong Kong, China; Department of Pathology, The University of Hong Kong, Hong Kong, China; Corresponding author
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  J. Zhou, X. Chen, Y. Xie, J. Li, N. Yamanaka, and X. Tong A differential diagnostic model of diabetic nephropathy and non-diabetic renal diseases Nephrol. Dial. Transplant., June 1, 2008; 23(6): 1940 - 1945. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Fine, A. Arepally, L. V. Hofmann, S. G. Mankowitz, and M. G. Atta Diagnostic utility and safety of transjugular kidney biopsy in the obese patient Nephrol. Dial. Transplant., July 1, 2004; 19(7): 1798 - 1802. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. H. Heine, U. Sester, M. Girndt, and H. Kohler Acanthocytes in the Urine: Useful tool to differentiate diabetic nephropathy from glomerulonephritis? Diabetes Care, January 1, 2004; 27(1): 190 - 194. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.-K. Mak, P.-N. Wong, K.-Y. Lo, G. M. W. Tong, and A. K. M. Wong Prospective study on renal outcome of IgA nephropathy superimposed on diabetic glomerulosclerosis in type 2 diabetic patients Nephrol. Dial. Transplant., June 1, 2001; 16(6): 1183 - 1188. [Abstract] [Full Text] [PDF]
|
|