NDT Advance Access originally published online on September 22, 2007
Nephrology Dialysis Transplantation 2007 22(12):3671; doi:10.1093/ndt/gfm489
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Serendipity
Email: stanley.shaldon{at}libello.comSir,
Allow me to amplify the comment on the use of the word serendipity by Dr Perrone [1]. Whilst it is generally accepted that the word was introduced into the English language by Walpole, it is possible that it had already been used by Dr Johnson, several years earlier. An old Persian tale relates to three princes who, when riding along country lanes in Ceylon, were used to making observations upon nature. One of them noticed that the grass had been eaten only on the left side of the path and concluded that a mule blind in his right eye had preceded them. Serendip was the old name for the island of Ceylon, today known as Sri Lanka. Whilst it is recognized that serendipity is one of the most difficult English words to translate, Dr Perrone's definition of its meaning would be clearer if the word intelligent was substituted for the original word sagacious, which is no longer in current use in English. This would lead to a more precise definition, being an intelligent deduction derived from an accidental observation. I am not sure that I can accept his example of its use to describe the phenomenon of contact activation with the original AN69 membrane. However, I do agree with his negative comments on the use of urea as a measure of dialysis adequacy.
Conflict of interest statement. None declared.
Nephrology
University Hospital of Nimes
25 Le Michelangelo
7 Avenue des Papalins
Monaco
References
- Perrone B. Serendipity: a necessity for the progress of dialysis therapy. Nephrol Dial Transplant (2007) 22(Suppl. 5):v37–v38. doi:10.1093/ndt/gfm297.
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