NDT Advance Access originally published online on September 30, 2009
Nephrology Dialysis Transplantation 2009 24(12):3893; doi:10.1093/ndt/gfp513
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Nephrol Dial Transplant 2009; doi:10.1093/ndt/gfp507E-mail: mark.guy@srft.nhs.uk
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Sir,
We thank Professors Park and Kim for their interest in our paper [1] and would agree that there can be pitfalls in the use of creatinine ratios. It would be expected that, as GFR declines, urine creatinine excretion would also diminish, thus potentially causing an overestimate of the protein-to-creatinine ratio (PCR). In our group of patients with chronic kidney disease
1 Department of Clinical Biochemistry, Salford Royal NHS Foundation Trust, Salford 2 Highover Park, Amersham, Bucks 3 Department of Renal Medicine Salford Royal NHS Foundation Trust, Salford 4 Department of Clinical Biochemistry, University of Oxford, Oxford, UK