NDT Advance Access originally published online on March 4, 2009
Nephrology Dialysis Transplantation 2009 24(6):1724-1726; doi:10.1093/ndt/gfp100
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© The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Predicting outcomes in CKD: the importance of perspectives, populations and practices
Division of Nephrology, University of British Columbia, Vancouver, Canada
Correspondence and offprint requests to: Adeera Levin, MD, FRCPC; E-mail: alevin@providencehealth.bc.ca
Keywords: eGFR; elderly populations; epidemiology; health care systems; outcomes
| The first 150 words of the full text of this article appear below. |
The problem of chronic kidney disease (CKD) has been brought into focus over the last 7 years since the publication and dissemination of the KDOQI definition, evaluation and classification of CKD guidelines, and the implementation of eGFR reporting by laboratories in numerous jurisdictions [1]. Together these two events have substantially increased awareness about and focus on CKD in both clinical and academic spheres. Concerns and issues have been raised as to the validity of the stages in all populations, the need for more refinement and the possibility of misclassification and inflated estimates of CKD in populations based on eGFR equations [2,3]. These discussions aside, the ability to report or calculate eGFR has improved the identification of abnormalities of kidney function in persons around the world, and stimulated substantial research into the validation of the equations in different populations, and prediction models for progression to renal replacement