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NDT Advance Access originally published online on January 31, 2009
Nephrology Dialysis Transplantation 2009 24(5):1388-1393; doi:10.1093/ndt/gfp003
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© The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Renal allograft thrombosis

Claudio Ponticelli1, Marco Moia2 and Giuseppe Montagnino3

1 Istituto Auxologico di Milano IRCCS 2 Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena IRCCS, Centro Emofilia e Trombosi A. Bianchi Bonomo 3 Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena IRCCS, U.O. Nefrologia e Dialisi, Milano, Italy

Correspondence and offprint requests to: Giuseppe Montagnino, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, U.O. Nefrologia e Dialisi, Via Commenda 15, 20122, Milan, Italy. Tel: +39-02-55034583-52; Fax: +39-02-55034570; E-mail: monta@policlinico.mi.it

Keywords: arterial thrombosis; renal transplantation; venous thrombosis

The first 150 words of the full text of this article appear below.



   Early graft thrombosis
 
Renal allograft thrombosis may be responsible for 2–7% of early allograft losses in adults [1] and up to 35% in children [2]. The North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) reported that graft thrombosis represented the main cause of graft failure in the first year. Most cases of renal allograft thrombosis occur early in the postoperative period with a peak incidence of 48 h. However, thrombus formation may be delayed until after the first week [3]. Thrombosis may initially involve the renal artery or more frequently the renal vein, but in some cases it is difficult to ascertain where the thrombosis originated.

Several factors may be involved in the pathogenesis of graft thrombosis. Thrombosis may be caused by technical errors, by vascular clamp injury or perfusion cannulation injury. Although vascular abnormalities in the donor kidney may be responsible for graft thrombosis [4. . . [Full Text of this Article]

Diagnosis
Prevention
Prognosis and treatment


   Late allograft thrombosis
 
Renal artery thrombosis
Renal vein thrombosis

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