Skip Navigation


NDT Advance Access originally published online on February 5, 2009
Nephrology Dialysis Transplantation 2009 24(5):1378-1383; doi:10.1093/ndt/gfp018
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
24/5/1378    most recent
gfp018v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Arneson, T. J.
Right arrow Articles by Gilbertson, D. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Arneson, T. J.
Right arrow Articles by Gilbertson, D. T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Comparison of methodologies to characterize haemoglobin variability in the US Medicare haemodialysis population

Thomas J. Arneson, David Zaun, Yi Peng, Craig A. Solid, Stephan Dunning and David T. Gilbertson

Chronic Disease Research Group, Minneapolis Medical Research Foundation, Minneapolis, MN, USA

Correspondence and offprint requests to: Thomas J. Arneson, Chronic Disease Research Group, Minneapolis Medical Research Foundation, 914 South 8th Street, Suite S-406, Minneapolis, MN 55404, USA. Tel: +1-612-347-5355; Fax: +1-612-347-5980; E-mail: tarneson@cdrg.org

Keywords: dialysis; haemoglobin levels; haemoglobin variability

The first 150 words of the full text of this article appear below.



   Introduction
 
Anaemia is a common complication of renal failure [1]; its appropriate management is an important aspect of dialysis patient care [2]. Due to developments in anaemia management over the past 20 years, average haemoglobin levels have risen steadily and transfusion needs declined [1]. The concern about what constitutes appropriate anaemia management has increased due to results from clinical trials [3–5] and increasing costs of treatment [1]. Considerable month-to-month haemoglobin level change has been demonstrated [1,6–8] and two recent studies, using different methods to characterize haemoglobin variability, came to different conclusions regarding the association between haemoglobin variability and mortality [9,10].

Though many studies have analysed haemoglobin level distributions within dialysis patient populations (inter-patient variability) [8,11–13], and some have used a measure of individual-level haemoglobin variability over time (intra-patient variability) as an . . . [Full Text of this Article]



   Methods
 
Data sources and study population


   Definition and application of the four methodologies
 
Standard deviation
Residual standard deviation
Fluctuations across thresholds
Haemoglobin cycling


   Discussion
 
Study strengths and limitations


   Conclusion
 

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?