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NDT Advance Access originally published online on December 15, 2008
Nephrology Dialysis Transplantation 2009 24(4):1103-1109; doi:10.1093/ndt/gfn691
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Ethnic advantages in kidney transplant outcomes: the Hispanic Paradox at work?

Elisa J. Gordon1,2 and Juan Carlos Caicedo2

1 Institute for Healthcare Studies 2 Department of Surgery, Division of Organ Transplantation, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA

Correspondence and offprint requests to: Elisa J. Gordon, Research Associate Professor, Institute for Healthcare Studies, Division of Organ Transplantation, Department of Surgery, Feinberg School of Medicine, Northwestern University, 750 N. Lake Shore Drive, 10th Floor, Chicago, IL 60611-3152. Tel: +312-503-5563; Fax: +312-503-2777; E-mail: e-gordon@northwestern.edu

Keywords: ethnic/racial disparities; graft survival; Hispanic Paradox; outcomes; renal transplantation

The first 150 words of the full text of this article appear below.



   Introduction
 
Kidney graft loss in the first 10 years following transplantation is a significant problem despite tremendous scientific advances in treating acute and chronic rejection. While short-term acute rejection has come under control with 1-year survival rates surpassing 91%, long-term graft survival remains inadequate [1]. The 3-year, 5-year and 10-year deceased donor unadjusted graft survival rates are 78.6%, 67.1% and 40.8%, respectively, among all kidney recipients in the United States (USA) [2].

The loss of transplanted grafts is a major public health problem. Kidney transplantation is the treatment of choice for most patients with end-stage renal disease (ESRD) since it provides a longer length of life, better quality of life [3,4] and is more cost-effective than dialysis [5,6]. When kidney grafts fail, patients return to dialysis, creating an even greater demand for scarce kidney (re-)transplants and further burdening society with greater costs [. . . [Full Text of this Article]


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