NDT Advance Access originally published online on July 23, 2009
Nephrology Dialysis Transplantation 2009 24(11):3284-3285; doi:10.1093/ndt/gfp368
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© The Author 2009. Published by Oxford University Press [on behalf of ERA-EDTA]. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Coumarin use in dialysis patients with atrial fibrillation—more harm than benefit?
Division of Nephrology and Clinical Immunology, RWTH University of Aachen, Germany
Correspondence and offprint requests to: Jürgen Floege; E-mail: juergen.floege@rwth-aachen.de
Keywords: atrial fibrillation; haemodialysis; warfarin
| The first 10% of the full text of this article appears below. |
Atrial fibrillation (AF) is the most common arrhythmia in haemodialysis (HD) patients. In the United States Renal Data System (USRDS) report, the prevalence in the American HD population is given as
10% [1]. The major risk associated with AF is the development of intraatrial thrombi with subsequent stroke or peripheral embolic events. Oral anticoagulation with coumarins is often initiated in AF patients, but its benefits must be weighed against bleeding complications. The CHADS2 score, which is part of the AHA (American Heart Association) and
| Data on coumarin use in HD patients with AF are scarce and inconclusive |
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| Coumarin therapy and vascular calcification |
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