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Dietary sodium and cardiovascular and renal disease risk factors: dark horse or phantom entry?
Department of Nutrition, University of California at Davis, CA, USA
Correspondence and offprint requests to: David A. McCarron, Academic Network, LLC, 120 NW 9th Avenue, Suite 216, Portland, OR 97209-3326, USA. Tel: +1-503-228-3217; Fax: +1-503-273-8778; E-mail: dmccarron@academicnetwork.com
Keywords: cardiovascular disease; dietary; risk factors; sodium
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Introduction |
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Identifying a nutritional cause of cardiovascular disease (CVD), a nutrient that could be manipulated to reverse CVD morbidity and mortality, would be finding the Holy Grail of nutrition and CV science. Cardiovascular researchers and public policy advocates have long labeled dietary sodium as this nutrient, what they consider the primary dietary factor in the pathogenesis of high blood pressure (BP) and subsequent CVD, despite the lack of valid scientific data to bear this out [1]. While Mimran et al. [2] promulgate this claim in their commentary in this issue, they fail to acknowledge the defects in their supporting evidence or the more carefully derived evidence demonstrating that dietary sodium holds no more than an ancillary, if any, role in the development of cardiovascular or renal disease in the general population. That assessment is not to suggest that the management of many patients with chronic kidney
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The short history of the race |
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The revisionist history of the race
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Have the bookies skewed the odds? |
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The home stretch |
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And the winner is... |
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Today's better bet |
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