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NDT Advance Access originally published online on September 22, 2008
Nephrology Dialysis Transplantation 2008 23(12):3746-3748; doi:10.1093/ndt/gfn532
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Illness trajectories: an important concept in the management of kidney failure

Fliss E. M. Murtagh1, Emma Murphy2 and Neil S. Sheerin3

1 Department of Palliative Care, Policy & Rehabilitation, King's College London, London SE5 9RJ 2 Renal Unit, Guy's and St Thomas’ NHS Foundation Trust, London SE1 9RT 3 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK

Correspondence and offprint requests to: Neil Sheerin, Institute of Cellular Medicine, 4th Floor, William Leech Building, Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. Tel: +44-191-222-7146; Fax: +44-191-222-0723; E-mail: neil.sheerin@ncl.ac.uk

Keywords: disease trajectory; end of life care; stage 5 chronic kidney disease

The first 10% of the full text of this article appears below.



   Introduction
 
The number of patients diagnosed with chronic kidney disease (CKD) is increasing, with recent studies suggesting that >10% of the population may have CKD [1,2]. This high prevalence is due to a variety of factors. A major contributor, in developed countries, is the increasing age of the population; epidemiological studies show that the prevalence of CKD increases dramatically with advancing age [2]. As the population lives longer and the proportion of older people increases, so the prevalence of CKD increases. In addition, use of estimated glomerular filtration rate (eGFR) has contributed to increased recognition of CKD [3]. Improved accessibility to renal services has also meant that many patients previously not referred are now being seen by nephrologists.

The presence of CKD has many implications for the patients, including increased morbidity . . . [Full Text of this Article]



   Disease trajectories
 


   Implications of disease trajectories
 


   Trajectories in renal disease
 


   Summary
 

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