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Nephrology Dialysis Transplantation 2007 22(Supplement 9):ix45-ix53; doi:10.1093/ndt/gfm449
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org



Speaker Abstracts

Tuesday, 6 February 2007

The first 150 words of the full text of this article appear below.

How common is early CKD?


 

How robust is eGFR as a measure for early CKD?

Edmund J. Lamb

Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent, UK, CT1 3NG

Correspondence to: Email: edmund.lamb@ekht.nhs.uk

Glomerular filtration rate (GFR) is accepted as the best overall measure of kidney function but measurement using reference procedures (e.g. 51Cr-EDTA) is impractical for large-scale application. Internationally there has been a recent thrust towards earlier detection of chronic kidney disease (CKD), primarily using estimated GFR (eGFR) as a tool [1]. Quality requirement one of Part 2 of the Renal NSF was aimed at prevention and early detection of CKD and to satisfy this it was recommended that clinical biochemistry laboratories report eGFR alongside all requests received for serum creatinine measurement in adults [2]. In April 2006, the Department of Health in England recommended universal eGFR reporting using the ID-MS standardized MDRD equation [3] with appropriate adjustment for assay differences and the Quality and Outcomes Framework (QOF) introduced a register of people in primary care with stages 3–5 CKD. Clinical practice guidelines to support these . . . [Full Text of this Article]

Damian G. Fogarty1,2

1Belfast City Hospital and 2Queen's University Belfast, Northern Ireland

Peter Murchie

Department of General Practice and Primary Care, University of Aberdeen

Eberhard Ritz

Ruperto-Carola University, Heidelberg, Germany

Chris Isles

Renal Unit, Dumfries and Galloway Royal Infirmary, Dumfries, DG1 4AP

Alan Jardine

BHF Glasgow Cardiovascular Research, University of Glasgow, Glasgow G12 8TA

David Goldsmith

Renal Unit, Guy's; Hospital, London SE1 9RT

Mike Cassidy

Nottingham Renal & Transplant Unit, Nottingham City Hospital, Nottingham NG5 1PB

Donal O’Donoghue

Hope Hospital, Salford M6 8HD

Natasha McIntyre

Nottingham University Hospital NHS Trust

Luke Vale

Health Economics Research Unit, University of Aberdeen

John Feehally

John Walls Renal Unit, Leicester General Hospital, Leicester

Meguid El Nahas

Sheffield Kidney Institute, Sheffield, UK


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