Nephrology Dialysis Transplantation 2007 22(5):i; doi:10.1093/ndt/gfm262
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In this issue ...
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Prorenin and the (pro)renin receptor: an update
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Prorenin is released constitutively from the kidneys and its
blood levels are
10-fold higher than those of renin. In microalbuminuric
diabetic subjects and pregnant women, prorenin is disproportionally
increased compared with renin. The origin and main functions
of prorenin are being discussed. The second part focuses
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Is there a future for costimulation blockade?
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The association of an aldosterone blocker and an ACE inhibitor additively suppresses renal TGF-ß and NADPH oxidase in Dahl salt-sensitive rats with heart failure
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Platelet-derived growth factor PDGF-D is widely expressed in fibrotic kidneys
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The traditional management of children with proteinuric kidney disease is treatment with high dose steroids regardless of comorbid conditions, such as obesity
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The occurrence of membranous nephropathy-following allogeneic haematopoietic stem cell transplantation is rare
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Endothelial injury via angiotensin II may mediate a hyperplastic and prothrombotic response in PTFE grafts
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A Markov model estimated the incremental cost-utility of cinacalcet in the UK
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