NDT Advance Access originally published online on January 25, 2007
Nephrology Dialysis Transplantation 2007 22(4):1007-1012; doi:10.1093/ndt/gfl822
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
From cold dialysis to isothermic dialysis: a twenty-five year voyage
Nephrology and Dialysis Unit, SM Annunziata Hospital Florence, Italy
Correspondence and offprint requests to: Dr Francesco Pizzarelli, Head of Nephrology Unit, SM Annunziata Hospital, Via dell Antella 58, 50011-Antella, Florence, Italy Email: fpizzarelli@yahoo.com
Keywords: cold dialysis; dialysis-related hyperthermia; isothermic dialysis; symptomatic hypotension; temperature
| The first 150 words of the full text of this article appear below. |
| Introduction |
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Twenty-five years have passed since our group described for the first time the role played by Temperature (T) in cardiovascular stability. Cold treatments prevented the hypotension induced by warm treatments, whether in haemodialysis (HD) or in isolated ultrafiltration [1] or in haemofiltration [2,3].
Though some notes of caution were sounded [4], all researchers studying the problem in the years that followed confirmed the role played by T in short-term [59] as well as in long-term studies [10,11]. As compared to standard HD or warm HD, that is with dialysate T of 3737.5°C, cold HD, that is with dialysate T of 3535.5°C, ensures better cardiovascular stability. In 1997, reduction of dialysate T was recommended by the DOQI Guidelines as a means to prevent intradialytic hypotension [12]. A systematic review recently published found that intradialytic
| Notions of physiology on the relations between body temperature and cardiocirculatory function |
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| Haemodynamic profile and dialytic efficiency in cold dialysis |
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| Determinants of thermal balance in dialysis |
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| Why does body T increase in standard dialysis? |
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| Who benefits from cold dialysis? |
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| The BTM |
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| From cold dialysis to isothermic dialysis |
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| Comparison of methods/methodologies for preventing hypotension |
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| Conclusions |
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