NDT Advance Access originally published online on January 5, 2007
Nephrology Dialysis Transplantation 2007 22(3):681-683; doi:10.1093/ndt/gfl735
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Is there really good news about pandemic diabetic nephropathy?*,
1Department of Medicine, Downstate Medical Center, Brooklyn, NY and 2Department of Surgery, Yale University, School of Medicine, New Haven, CT, USA
Correspondence and offprint requests to: Eli A. Friedman, MD, Department of Medicine, Downstate Medical Center, 450 Clarkson Avenue Brooklyn, New York 11203, USA. Email: elifriedmn@aol.com
Keywords: diabetes; diabetic nephropathy; end stage renal failure (ESRD); epidemiology; pandemic; renoprotection; uraemia; USRDS
| The first 10% of the full text of this article appears below. |
Defined in the dictionary as an adjective, the word pandemic, meaning: occurring over a wide geographic area and affecting an exceptionally high proportion of the population, like epidemic, has evolved to its current usage as a noun [1]. In 2005, growth in number of individuals in the United States treated for end-stage renal disease (ESRD) was analysed using data generated by the United States Renal Data system (USRDS), sustaining the conclusion that most of the expansion was due to a three-fold increase in risk of ESRD in people with diabetes and therefore, qualifies as an epidemic (Figure 1) [2]. Examination of the epidemic growth curve of diabetes [3] pointed to diabetes mellitus as the leading cause of ESRD (i.e. kidney failure requiring dialysis or transplantation) in the United States, accounting for 44% of new cases of treated ESRD in
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