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NDT Advance Access originally published online on January 5, 2007
Nephrology Dialysis Transplantation 2007 22(3):681-683; doi:10.1093/ndt/gfl735
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Is there really good news about pandemic diabetic nephropathy?*,{dagger}

Eli A. Friedman1 and Amy L. Friedman2

1Department of Medicine, Downstate Medical Center, Brooklyn, NY and 2Department of Surgery, Yale University, School of Medicine, New Haven, CT, USA

Correspondence and offprint requests to: Eli A. Friedman, MD, Department of Medicine, Downstate Medical Center, 450 Clarkson Avenue Brooklyn, New York 11203, USA. Email: elifriedmn@aol.com

Keywords: diabetes; diabetic nephropathy; end stage renal failure (ESRD); epidemiology; pandemic; renoprotection; uraemia; USRDS

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Defined in the dictionary as an adjective, the word pandemic, meaning: ‘occurring over a wide geographic area and affecting an exceptionally high proportion of the population,’ like epidemic, has evolved to its current usage as a noun [1]. In 2005, growth in number of individuals in the United States treated for end-stage renal disease (ESRD) was analysed using data generated by the United States Renal Data system (USRDS), sustaining the conclusion that most of the expansion ‘was due to a three-fold increase in risk of ESRD in people with diabetes and therefore, qualifies as an epidemic (Figure 1) [2].’ Examination of the epidemic growth curve of diabetes [3] pointed to diabetes mellitus as the leading cause of ESRD (i.e. kidney failure requiring dialysis or transplantation) in the United States, accounting for 44% of new cases of treated ESRD in . . . [Full Text of this Article]


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