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Nephrology Dialysis Transplantation 2007 22(10):i; doi:10.1093/ndt/gfm609
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org


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Ciclosporin-induced hypertension is associated with increased sodium transporter of the loop of Henle. This elegant study further elucidates the mechanisms of ciclosporin-induced hypertension, by demonstrating that renal sodium and water retention is associated with an increase in the Na-K-2Cl co-transporter of the loop of Henle (NKCC2). This rise in protein is associated with an increase in NKCC2 . . . [Full Text of this Article]


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