Skip Navigation


NDT Advance Access originally published online on September 12, 2006
Nephrology Dialysis Transplantation 2007 22(1):40-42; doi:10.1093/ndt/gfl544
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
22/1/40    most recent
gfl544v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Peters, H.
Right arrow Articles by Unger, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Peters, H.
Right arrow Articles by Unger, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Mast cells and the power of local RAS activation*

Harm Peters1,2 and Thomas Unger1,3

1Center for Cardiovascular Research, 2Department of Nephrology, 3Institute for Pharmacology and Toxicology, Charité Universitätsmedizin Berlin, Charité Campus Mitte, Humboldt University, Berlin, Germany

Correspondence and offprint requests to: Harm Peters, MD, Department of Nephrology, Charité Universitätsmedizin Berlin, Charité, Campus Mitte, Humboldt University, Charitéplatz 1, D-10098 Berlin, Germany. Email: Harm.Peters@charite.de

Keywords: cardiac dysrhythmia; local RAS; mast cells; renin

The first 10% of the full text of this article appears below.

More than 100 years ago, mast cells were discovered and named by Paul Ehrlich, who was the first to recognize this well-fed appearing cell loaded with huge cytoplasmic granules in various tissues [1]. Mast cells derive from CD34+ multipotent bone marrow progenitor cells which circulate in small numbers in the blood as basophilic leucocytes, and enter the mucosal surfaces and connective tissue compartments of multiple organs [2]. This distinct cell type is today best known for its key role in immunoglobulin-E-mediated allergic reactions such as bronchial asthma and anaphylactic reactions. More recently, however, mast cells have been found to be . . . [Full Text of this Article]



   Mast cell renin expression
 


   Mast cell renin function
 


   The power of mast cells
 


   Mast cells in kidney disease
 


   Renal mast cells may act profibrotic
 

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Am. Soc. Nephrol.Home page
S. R. Holdsworth and S. A. Summers
Role of Mast Cells in Progressive Renal Diseases
J. Am. Soc. Nephrol., December 1, 2008; 19(12): 2254 - 2261.
[Abstract] [Full Text] [PDF]