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NDT Advance Access originally published online on November 8, 2006
Nephrology Dialysis Transplantation 2007 22(1):12-14; doi:10.1093/ndt/gfl587
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Sudden cardiac death in nephrology: focus on acquired long QT syndrome

Ihor Gussak1 and Hiie M. Gussak2

1eResearchTechnology, Global Medical Affairs and UMDNJ-RWJMS, Bridgewater and 2Hackensack University Medical Center, Hackensack, NJ, USA

Correspondence and offprint requests to: Ihor Gussak, MD, PhD, FACC, eResearchTechnology, Global Medical Affairs and UMDNJ-RWJMS, Bridgewater, NJ, USA. Email: igussak@ert.com

Keywords: acquired long QT syndrome; nephrology; sudden cardiac death

The first 150 words of the full text of this article appear below.



   Introduction
 
More than a half million Americans have end-stage renal diseases (ESRD), 20 millions have been diagnosed with chronic kidney disease (CKD) and another 20 millions are individuals at risk [1]. The ESRD patients population is characterized as one with the highest mortality rate (even when adjusted for age, race, sex and comorbid conditions), comparable with patients in advanced stages of breast cancer [2]. Among dialysis patients in the United States, cardiovascular disease (CVD) mortality is 30 times higher than in general population and accounts for 58% of all-cause mortality, and the risk for arrhythmogenic death is one of the highest among any other populations [3]. The situation is greatly exacerbated by the fact that there is a clinically proven lack of benefits from: (a) implantable cardioverter-defibrillators in patients with severe renal disease and heart failure [4], and (b) the statins on the . . . [Full Text of this Article]



   Acquired long QT syndrome in nephrology
 


   Arrhythmogenic potentials of acquired long QT syndrome and haemodylisis
 


   Conclusions
 

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