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Nephrology Dialysis Transplantation 2006 21(Supplement 5):v1-v3; doi:10.1093/ndt/gfl473
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

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David Goldsmith

Guy's Hospital, London, UK

Correspondence and offprint requests to: David Goldsmith, Renal Unit, 6th Floor Guy's Hospital, London SE1 9RT, UK. Email: david.goldsmith@gstt.nhs.uk

Keywords: biopharmaceuticals; biosimilars; comparative testing; immunogenicity; pharmacovigilance; regulatory guidelines

The first 10% of the full text of this article appears below.

We are now in the fifth decade of providing clinically useful medical and surgical care for patients with chronic kidney disease (CKD). The numbers of patients requiring a plan for renal replacement therapy has risen very sharply, as has the number of patients with a recognized impairment of kidney function. Progress in medicine, increasing economic wealth in industrialized and developing countries, societal pressures and above all the significant growth of a large ‘ageing’ cohort (prone to obesity, hypertension, diabetes and cardiovascular disease) . . . [Full Text of this Article]


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