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NDT Advance Access originally published online on April 6, 2006
Nephrology Dialysis Transplantation 2006 21(6):1486-1488; doi:10.1093/ndt/gfl087
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Translational Nephrology

Xenograft rejection—all that glitters is not Gal

Ben Sprangers, Mark Waer and An D. Billiau

Laboratory of Experimental Transplantation, University of Leuven, Leuven, Belgium

Correspondence and offprint requests to: Mark Waer, Laboratory of Experimental Transplantation, University of Leuven, Campus Gasthuisberg, O&N 811, Herestraat 49, B-3000 Leuven, Belgium. Email: mark.waer@med.kuleuven.be

Keywords: xenotransplantation; kidney; GAL

The first 10% of the full text of this article appears below.

Xenotransplantation is being developed in the hope of resolving the critical shortage of donor organs for transplantation. The Eurotransplant waiting lists [1] for donor organs of various kinds number almost 16 000 patients and the US lists [2] more than 90 000 patients. Renal transplantation, for instance, cost-effectively confers a significant survival advantage [3] and improvement of quality of life [4]. But whereas currently, in Europe, nearly 12 000 end-stage renal disease patients await a suitable donor, only 3383 kidney transplants were performed in 2005, with an average waiting time of 1174 days [1]. Substantial research efforts are being made in the field of xenotransplantation, and the immunological barriers are gradually being elucidated. Pig-to-human xenogeneic . . . [Full Text of this Article]


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Home page
 Nephrol Dial TransplantHome page
D. K. C. Cooper
Xenotransplantation--will tolerance be essential?
Nephrol. Dial. Transplant., October 1, 2006; 21(10): 2991 - 2992.
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