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Nephrology Dialysis Transplantation 2006 21(6):1461-1464; doi:10.1093/ndt/gfi317
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Editorial Comment

The epidemic of renal disease—what drives it and what can be done?

William M. McClellan1,2

1 Department of Internal Medicine, Section of Nephrology and 2 Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA

Correspondence and offprint requests to: William M. McClellan, Email: bmcclell@gmcf.org

Keywords: epidemiologic transition; ESRD; primary prevention; secondary prevention

The first 150 words of the full text of this article appear below.

Contemporary societies are in the midst of an epidemic of end-stage renal disease (ESRD). The epidemic is partially a consequence of profound gains in life span that occurred in economically developed world regions beginning in the 19th century, where life expectancy at birth increased during the 20th century on average at 2–3 months per year [1]. This remarkable achievement has been termed the epidemiologic transition and is partially attributable to a stage of better nutrition and a second stage characterized by control of infection [2]. A welcome consequence of these two stages of the epidemiologic transition has been improved survival during childhood and young adulthood as is illustrated by China (Figure 1), where the traditional pyramid has been transformed to a ‘population box’ [3,4].


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  		Fig. 1. Estimated year 2000 and projected year 2025 population structures for China demonstrating the impact of the . . . [Full Text of this Article]

 

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