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NDT Advance Access originally published online on May 17, 2005
Nephrology Dialysis Transplantation 2005 20(8):1539-1541; doi:10.1093/ndt/gfh885
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© The Author [2005]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

Editorial Comment

Peritonitis: limiting the damage

Edwina A. Brown

Faculty of Medicine, Imperial College London, Charing Cross Campus, London, UK

Correspondence and offprint requests to: Professor Edwina A. Brown, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK. Email: e.a.brown@imperial.ac.uk

Keywords: peritoneal dialysis; peritonitis

The first 150 words of the full text of this article appear below.



   Introduction
 
Reducing the morbidity associated with peritonitis is one of the major challenges to improve outcomes for patients on peritoneal dialysis (PD). In the short-term, during the actual episode, patients suffer pain, risk of hospitalization and social inconvenience, with extra and often numerous hospital visits. In one series, peritonitis accounted for 25% of hospital admissions for patients on PD [1]. In the long term, peritonitis is a major cause of patients transferring to haemodialysis, accounting for 13–54% of technique failure in long-term continuous ambulatory peritoneal dialysis (CAPD) patients [2] and 43% of patients on automated peritoneal dialysis (APD) [3]. Even in patients who recover from the initial episode, peritonitis causes other long-term sequelae, such as changes in membrane permeability and sclerosing peritonitis, which eventually contribute to technique failure.

Severe or repeated episodes of peritonitis are particularly damaging to the peritoneal membrane. Davies et al. [. . . [Full Text of this Article]



   Reducing the incidence of peritonitis
 


   Reducing morbidity and hospitalization
 


   Improving the cure rate
 


   Reducing the inflammatory response of the membrane
 


   Appropriate removal of the catheter with non-responding peritonitis
 


   Conclusion
 

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