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Nephrology Dialysis Transplantation 2005 20(4):684-687; doi:10.1093/ndt/gfh777
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© The Author [2005]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

Personal Opinion

Fistula maturation: doesn't time matter at all?

Giuliano Brunori1, Pietro Ravani2, Salvatore Mandolfo3, Enrico Imbasciati3, Fabio Malberti2 and Giovanni Cancarini1

1 Cattedra di Nefrologia Università di Brescia, Brescia, 2 Divisione di Nefrologia e Dialisi, Cremona and 3 Divisione di Nefrologia e Dialisi, Lodi, Italy

Correspondence and offprint requests to: Dr Giuliano Brunori, Chair and Department of Nephrology, University and Spedali Civili; Piazza Ospedale 1, 25123 Brescia, Italy. Email: gcbrunori@hotmail.com

The first 150 words of the full text of this article appear below.



   Introduction
 
The arterio-venous fistula (AVF) remains the ‘gold standard’ access to haemodialysis, showing better survival and lower complication rates than graft and catheters. However, fistulae are not readily usable after creation, and recommendations for optimal waiting time before use are based upon observational studies. The current guidelines suggest a minimum of 1 month and preferably 2–3 months before utilization of an AVF [1]. However, recently published findings from two large studies, the DOPPS and an Italian multi-centre study, reached different conclusions [2–4]. Those investigations tested the role of the maturation time, i.e. the time period from AVF creation and the first cannulation (FCT), as prognostic factor for AVF failure. Because of substantial differences in the ‘measurement method’ applied, discussion on methodological features of those prognostic studies may contribute to a more careful interpretation of their findings.



   DOPPS studies
 
The most recent report on the relationship between maturation time and . . . [Full Text of this Article]



   The Italian multi-centre study
 


   Final remarks
 

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