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Nephrol Dial Transplant (2003) 18: 1248-1252
© 2003 European Renal Association-European Dialysis and Transplant Association

Editorial Comment

Is it really good to be fat on dialysis?

Abdulla K. Salahudeen

Department of Medicine, Nephrology Division, University of Mississippi Medical Center, Jackson, MS, USA

Keywords: BMI; dialysis; nutrition; obesity; risk factors; survival

The first 150 words of the full text of this article appear below.

Introduction

Factors associated with higher cardiovascular mortality in the general population may exhibit a paradoxical relationship with patients on dialysis. This ‘dialysis-risk paradox’ has been reported for high blood pressure, serum lipids and body mass [1–11]. The finding, however, is more consistent and persuasive for obesity [4–7].

Relationship between body mass and survival on haemodialysis

The paradoxical observation of a lack of mortality increase with higher body mass index (BMI) in dialysis patients was first reported from France by the Diaphane collaborative study [12]. In 1998, Leavey et al. [13], while assessing the influence of a number of commonly used clinical parameters on dialysis survival, confirmed the association between low BMI and increased mortality in patients on haemodialysis. They also reported an absence of mortality risk in patients with higher BMI values. However, a study by our group, published in 1999, identified for the first time . . . [Full Text of this Article]

Relationship between body mass and survival on peritoneal dialysis

Body mass, race and dialysis doses

Obesity-survival advantage in sick patients without renal failure

Plausible mechanisms of obesity-associated survival advantage

Implication for clinical practice


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