Nephrol Dial Transplant (2003) 18: 1061-1065
© 2003 European Renal Association-European Dialysis and Transplant Association
Personal Opinion
Dose of dialysis, convection and haemodialysis patients outcome—what the HEMO study doesn't tell us: the European viewpoint
Department of Nephrology and Dialysis, A. Manzoni Hospital, Lecco, Italy
Keywords: convection; dialysis adequacy; dialysis dose; dialysis morbidity and mortality; multicentre trial
| The first 150 words of the full text of this article appear below. |
The main aims of dialysis treatment are to prolong patient survival, reduce morbidity and improve quality of life. However, despite many technical advances made over the last few years, morbidity and mortality of dialysis patients remain unacceptably high [1] and their quality of life is often poor.
The delivered dose of dialysis can affect morbidity and mortality of dialysis patients [2]. Moreover, in the last decade, several epidemiological studies, based mainly on longitudinal database registries, have suggested a possible superiority of convective dialysis treatments in improving patient outcome [3–7]. Thus, in addition to the dose of dialysis delivered, the size of molecules removed can also be of importance. In a randomized controlled study of 380 patients, Locatelli et al. [8] compared four dialysis modalities (cuprophan dialysis, low- and high-flux polysulfone dialysis, and high-flux polysulfone haemodiafiltration). While there was no
Dialysis dose
Dialysis dose and treatment failure: the National Cooperative Dialysis Study
Dialysis dose and mortality
Dialyzer flux
The HEMO study
Design and methods
Results
Study sample selection bias
Dialysis parameters
Body water volume
Prevalent patients
Statistical evaluation
Membrane Permeability Outcome study
Conclusions
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Connotea 
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