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Nephrol Dial Transplant (2003) 18: 1052-1058
© 2003 European Renal Association-European Dialysis and Transplant Association

Invited Comment

Skin cancers after transplantation

Brigitte Dreno

Centre Hospitalier Universitaire, Clinique Dermatologique, Nantes, France

Keywords: carcinoma; lymphoma; melanoma; renal transplantation; skin cancers

The first 150 words of the full text of this article appear below.

Renal transplantation has been performed for more than 35 years with a large success. However, the organ tolerance has to be associated with the induction and the maintenance of an immunosuppressive status in the patient which induces the development of skin cancers. Skin cancers are considered to be the most frequent tumours in transplant patients.

The incidence of skin cancer is increased in transplant recipients as compared to the general population and varies according to the country concerned. Thus, Hartevelt et al. [1] found a cumulative incidence of skin cancer, ranging from 10 to 40% at 10 and 20 years after transplantation. This incidence is higher in Australians, 45 and 70% at 10 and 20 years, respectively, after the transplantation. This fact is related to more intense sun exposure at these latitudes. Among the skin cancers, cutaneous premalignant and malignant epithelial lesions (carcinoma) are the most frequent . . . [Full Text of this Article]

Carcinoma

Premalignant cutaneous lesions
Squamous-cell carcinoma and basal-cell carcinoma
Cutaneous lymphomas

Cutaneous B-cell lymphoma
Cutaneous T-cell lymphoma
Naevi and melanoma

Naevi
Melanoma (Figure 7Go)
Kaposi's sarcoma

Epidemiology
Clinical features
Histology
Staging
Treatment
Rare skin cancers

Merkel cell carcinoma
Vascular cutaneous tumour
Mesenchymal cutaneous tumours
Adnexal gland carcinoma
Conclusion


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