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Nephrol Dial Transplant (2003) 18: 471-476
© 2003 European Renal Association-European Dialysis and Transplant Association

Invited Comment

Age and renal transplantation: an interim analysis

Gabriele Schratzberger and Gert Mayer

University Hospital, Department of Internal Medicine, Division of Nephrology, Innsbruck, Austria

Keywords: age; donor; kidney; recipient; renal transplantation

The first 150 words of the full text of this article appear below.

Introduction

The life expectancy of the population in general is increasing consistently, as is the age of the dialysis population. Consequently, donors and recipients are getting older, and renal transplantation has become a therapy that is not limited to the youngest segment of subjects with terminal renal failure. Reluctance to use organs from elderly subjects has decreased with increasing demand (and possibly with increasing age of transplant physicians), and age-matching programmes have been developed to better serve the dialysis population. The medical aspects of this changing attitude continue to be explored. However, the answers obtained may be the starting point for a discussion of oncoming ethical problems.

Effect of donor age on outcome (Figure 1Go)

In the period from 1977 to 1982, a donor age >30 years was a major reason for declining a cadaver kidney allograft offer [11]. While 15% of kidneys retrieved from 16–20-year-old donors were not transplanted, the discard rate was 30 and 56% . . . [Full Text of this Article]

Effect of recipient age on outcome (Figure 2Go)

Age matching in renal transplantation

Is there something special about immunology in elderly grafts/recipients?


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