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Nephrol Dial Transplant (2003) 18: 249-252
© 2003 European Renal Association-European Dialysis and Transplant Association

Editorial Comment

Arterial pressure components and cardiovascular risk in end-stage renal disease

Carmine Zoccali

Division of Nephrology, Dialysis and Transplantation and CNR Centre of Clinical Physiology, Reggio Cal, Italy

Keywords: arterial stiffening; cardiovascular risk; end-stage renal disease; hypertension; left-ventricular hypertrophy; uraemia

The first 150 words of the full text of this article appear below.

Introduction

Hypertension is an established, strong trigger of cardiovascular events. However, the relative importance of its various components remains unclear. The prognostic value of hypertension in patients with end-stage renal disease (ESRD) has long been taken for granted and for this reason there is a paucity of high-quality studies in this area. There are very few prospective studies aimed at clarifying the impact of arterial pressure components on the incidence of cardiovascular complications in ESRD. Uncertainty enshrouds the optimal timing of blood-pressure (BP) measurement in relation to dialysis treatment, the threshold for treatment and the prognostic usefulness of 24-h ambulatory monitoring. In this brief review I will touch upon these important, unresolved arterial-pressure issues in ESRD.

Systolic, diastolic or pulse pressure?

Diastolic BP depends on peripheral vascular resistance and on central artery stiffness. High peripheral vascular resistance raises diastolic pressure while high arterial stiffness has an opposite influence on this component so that the relative contribution . . . [Full Text of this Article]

Arterial rigidity and arterial pressure components in ESRD

Pre-dialysis and post-dialysis arterial pressure and 24-h ambulatory monitoring

Is there any threshold for treatment in ESRD?


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