Nephrol Dial Transplant (2003) 18: 23-26
© 2003 European Renal Association-European Dialysis and Transplant Association
Editorial Comments
The living kidney donor: giving life, avoiding harm
1 Department of Medicine, Division of Nephrology, 2 Department of Medical Psychology and 3 Department of Urology, University of Heidelberg, Heidelberg, Germany
Keywords: hypertension; kidney; living-related; renal disease; transplantation; uninephrectomy
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Introduction
During the past 12 years, the time spent on the waiting list for renal transplantation rose progressively in the Eurotransplant area and specifically in Germany, whilst during the same time period, unfortunately, the number of cadaveric kidneys available for transplantation did not increase (Table 1
). In the face of a crushing organ shortage, nephrologists in Mid Europe have resorted increasingly to living-related or unrelated kidney donation in order to increase the number of grafts available. In our unit in Heidelberg, the proportion of living-related renal allografts increased from 11% in 1991 to 21% in 2001.
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In contrast, in Scandinavia, there has been a long tradition of living-related renal transplantation dating back more than 30 years. Single centre reports from Sweden have summarized outcomes of no less than 177 living donor nephrectomies from 1996 to
Living-related renal transplantation: beyond expanding the donor pool
What are the short-term and long-term risks of living-related kidney donation?
Evaluation of potential kidney donors (Table 2
)
Renal function
Hereditary renal diseases
Diabetes mellitus
Hypertension
Anatomical and functional evaluation of donor kidneys
Immunological evaluation
Viral infection
Malignancy
The marginal donor
Psychological evaluation
Social and legal aspects
Summary