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Nephrol Dial Transplant (2002) 17: 717-718
© 2002 European Renal Association-European Dialysis and Transplant Association


Controversies

Should the allocation of cadaveric kidneys for transplantation be based on HLA matching?

Robert A. P. Koene

Department of Nephrology, University Medical Centre Nijmegen, The Netherlands

Keywords: HLA matching; transplantation

In 1996 the European centres participating in the Eurotransplant organization agreed to the implementation of a new allocation system for kidneys of postmortal donors (Eurotransplant Kidney Allocation System, ETKAS). The proposed procedure was based on the following five criteria: HLA mismatch grade, waiting time, mismatch probability (a correction factor increasing the chances for patients with uncommon HLA phenotypes and for homozygous or immunized patients), local transplants (kidneys are shipped only if the HLA match is at least two match grades better than the best compatible local patient), and import–export balance per centre. In the course of time several changes have . . . [Full Text of this Article]

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