Nephrol Dial Transplant (2002) 17: 701-703
© 2002 European Renal Association-European Dialysis and Transplant Association
Editorial Comments
Percutaneous coronary interventions in patients with renal failure: overcoming in-stent restenosis?
Department of Internal Medicine, Division of Cardiology, University of Heidelberg, Heidelberg, Germany
Keywords: end-stage renal disease
Introduction
Patients with end-stage renal disease (ESRD) have a 20- to 40-fold higher cardiovascular mortality than patients without renal disease [1]; 52% of dialysis patients surviving an acute myocardial infarction die from a cardiac cause within the following 2 years [2]. This very unfavourable prognosis of ischaemic heart disease in dialysis patients is not only due to the severity of coronary artery disease, but may also reflect the underutilization of modern treatment measures for acute myocardical infarction [1,2].
One of the reasons for the underutilization of coronary revascularization procedures in the ESRD population may be the perception that patients with chronic renal failure (CRF) benefit less from coronary angiography, as they often have diffusely calcified coronary artery disease, which is neither suited to percutaneous nor to surgical revascularization. Nevertheless, several studies have shown that surgical revascularization has a
Stenting
Inhibition of platelet function
Management of restenosis
Notes
References