Nephrol Dial Transplant (2002) 17: 353-355
© 2002 European Renal Association-European Dialysis and Transplant Association
Editorial Comments
Managing big issues on lean evidence: treating obesity hypertension
Franz-Volhard-Klinik, Charité and Max-Delbrück Centre for Molekular Medicine, Berlin-Buch, Germany
Keywords: body weight; hypertension; obesity; therapy; treatment; weight gain
Introduction
Obesity, defined as a body mass index (BMI) greater than 30 kg/m2, is an important risk factor for hypertension, and excess adiposity is believed to account for 70% of hypertension in men and 60% in women [1,2]. There is now accumulating evidence that adipose tissue may itself be involved directly in the pathogenesis of hypertension, not only by contributing to an increase in sympathetic activity [3], but also to sodium and volume retention [4].
Obesitya risk factor neglected by current guidelines
Current guidelines for the management of hypertension provide specific recommendations for a variety of special patient populations, including patients with diabetes mellitus, coronary
Antihypertensive treatment of the obesebeyond weight loss
Why specific recommendations for obese hypertensive patients?
Selection of antihypertensive agents in the obese
Conclusion
Notes
References
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