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Nephrol Dial Transplant (2002) 17: 353-355
© 2002 European Renal Association-European Dialysis and Transplant Association


Editorial Comments

Managing big issues on lean evidence: treating obesity hypertension

Arya M. Sharma and Stefan Engeli

Franz-Volhard-Klinik, Charité and Max-Delbrück Centre for Molekular Medicine, Berlin-Buch, Germany

Keywords: body weight; hypertension; obesity; therapy; treatment; weight gain

Introduction

Obesity, defined as a body mass index (BMI) greater than 30 kg/m2, is an important risk factor for hypertension, and excess adiposity is believed to account for 70% of hypertension in men and 60% in women [1,2]. There is now accumulating evidence that adipose tissue may itself be involved directly in the pathogenesis of hypertension, not only by contributing to an increase in sympathetic activity [3], but also to sodium and volume retention [4].

Obesity—a risk factor neglected by current guidelines

Current guidelines for the management of hypertension provide specific recommendations for a variety of special patient populations, including patients with diabetes mellitus, coronary . . . [Full Text of this Article]

Antihypertensive treatment of the obese—beyond weight loss

Why specific recommendations for obese hypertensive patients?

Selection of antihypertensive agents in the obese

Conclusion

Notes

References


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