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Nephrol Dial Transplant (2002) 17: 2014-2016
© 2002 European Renal Association-European Dialysis and Transplant Association

Case Reports

Two different glomerular diseases in the same patient at an interval of 7 years

Giovanni M. Frascà1,, Letizia Soverini1, Paola Preda2, Gianandrea Pasquinelli2, Claudio Orsi1, Rita Prandini1, Alba Vangelista1 and Sergio Stefoni1

1 Nephrology, Dialysis and Renal Transplantation Unit and 2 Electron Microscopy Unit, Pathology Department, St Orsola University Hospital, Bologna, Italy

Keywords: double glomerulopathy; IgA nephritis; membranous glomerulonephritis

The first 10% of the full text of this article appears below.



   Introduction
 
Overlapping of different glomerulopathies has already been observed in renal biopsies from diabetic as well as non-diabetic patients [1]. Unlike other reports, the present paper describes a patient where two distinct forms of immunological glomerulonephritis with a different histological and clinical picture occurred separately at some years’ interval from each other. This finding suggests an individual susceptibility of the patient to immunological renal injury and gives food for speculation on the pathogenesis of glomerulonephritis.



   Case
 
The patient here described was born in Southern Italy in 1966. Family investigation proved negative for glomerular diseases, renal failure, arterial hypertension and diabetes mellitus. In 1991, when he was 25 years old, he had an episode of macroscopic haematuria during an upper airways infection, and this recurred in November 1994, at the age of 28. At that time, urinalysis revealed haematuria . . . [Full Text of this Article]



   Discussion
 

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