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Nephrol Dial Transplant (2002) 17: 1878-1882
© 2002 European Renal Association-European Dialysis and Transplant Association

Editorial Comments

Peritoneal-dialysis-related peritonitis: the art of rope-dancing

Wim Van Biesen, Nic Veys, Raymond Vanholder and Norbert Lameire

Renal Division, University Hospital Ghent, Belgium

Keywords: antibiotics; peritoneal dialysis; peritonitis; review

The first 150 words of the full text of this article appear below.

Introduction

Although incidence rates of peritonitis have decreased substantially with the introduction of the flush-before-fill double-bag principle, and the emergence of improved connection systems [1], peritonitis remains an Achilles tendon for peritoneal dialysis (PD) [2]. Mortality directly related to peritonitis is low, but peritonitis episodes cause psychosocial problems and are in the long run related to both technique failure and mortality [3]. Repetitive or protracted peritonitis episodes can also damage the peritoneal membrane [4]. Despite the overall decreasing incidence of peritonitis, mortality and technique failure attributable to it did not improve. This is due to the greater severity of infections caused by Gram-negative and Staphylococcus aureus infections, two types of infections that are less related to connection systems, and the incidence of which has remained stable [5]. Although infection rates in haemodialysis are at least as high as those in PD . . . [Full Text of this Article]

Local epidemiology

Pharmacokinetics, pharmacodynamics and clinical effectiveness

Prevention of peritonitis

Conclusions


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