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Nephrol Dial Transplant (2001) 16: 1550-1554
© 2001 European Renal Association-European Dialysis and Transplant Association

Invited Comment

Ambulatory blood pressure monitoring: fancy gadgetry or clinically useful exercise?

Eberhard Ritz, Vedat Schwenger, Martin Zeier and Ivan Rychlik1

Department of Internal Medicine, Ruperto Carola University, Heidelberg, Germany

Keywords: antihypertensive treatment; blood pressure; circadian blood pressure; progression of renal failure; renal transplantation

Ambulatory blood pressure—what is normal?

According to Verdecchia et al. [1], the average awake blood pressure (BP) by ambulatory BP measurement (ABPM) is normally <=130/80 mmHg. Values >=135/85 mmHg should be considered as diagnostic for the presence of ‘hypertension’. Similarly, based on a meta-analysis of numerous studies, Staessen et al. [2] found that the 95th percentile of normal BP values is 130/80 mmHg for average 24-h pressure values and 135/85 mmHg or 120/70 mmHg for day-time and night-time pressure values respectively. A decrease of nocturnal BP by <10% (or according to the more rigorous definition by <15%), is considered as `non-dipping’. Although gender and age are expected to affect circadian BP profile, these confounders are not considered in the above preliminary threshold values for untreated patients. No well-documented information is available on target BP values in patients on antihypertensive treatment.

Circadian blood pressure in renal patients

Most [3–5], but not all . . . [Full Text of this Article]

Why is the circadian blood pressure profile abnormal in renal patients?

Does circadian blood pressure profile affect renal prognosis?

Does the circadian blood pressure profile affect survival?

Is abnormal BP profile reversible after renal transplantation?

When to measure ambulatory blood pressure and what consequences to draw from the results?

Notes

References


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