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Nephrol Dial Transplant (2000) 15: 1293-1297
© 2000 European Renal Association-European Dialysis and Transplant Association

Invited Comments

Renal disease in Australian Aborigines

Wendy Hoy

Menzies School of Health Research, Darwin, Northern Territory, Australia

Introduction

In this era of increasing accountability in population-based research, and demands for strong evidence base of clinical practice, we need to examine justifications for the study of catastrophic problems in indigenous or transitional people. One justification might be the illumination of risk factors for, and mechanisms of, disease that can be generalized to the broader population, where they might be obscured by lower disease rates and density of risk factors. A more important justification is to arrive at, and model, solutions. We report a programme which has happily done both.

Australian Aborigines are a disenfranchized and marginalized people in a crisis of epidemiologic transition. Most Aborigines in the Northern Territory of Australia live in remote areas, in serious poverty and disadvantage, with inadequate services of all types. Standardized adult mortality rates are more than four times that of non-Aboriginal Australians, with all major conditions, including cardiovascular disease, represented in excess . . . [Full Text of this Article]

Rates and associations of renal disease

Natural history of renal disease

Renal size and renal morphology

Family clustering of renal disease

Health services and disease expression

Pharmacologic renal and cardiovascular protection

Conclusions

Acknowledgments

Notes

References


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