Nephrol Dial Transplant (2000) 15: 1281-1284
© 2000 European Renal Association-European Dialysis and Transplant Association
Editorial Comments
Changing patterns of antibiotic resistanceupdate on antibiotic management of the infected vascular access
1 Department of Internal Medicine, Division of Infectious Diseases and 2 Department of Microbiology, University Hospital, Ghent, Belgium
Introduction
Haemodialysis can be performed either through permanent arteriovenous (a-v) access, such as a fistula or a graft, or through temporary catheter access. Infection associated with haemodialysis catheters has emerged as one of the most prominent and most serious complications encountered in dialysis patients, and remains a significant cause of morbidity and mortality. This editorial is aimed at providing an update on changing management attitudes towards the infected vascular access as well as on changing patterns of antibiotic resistance, due to shifts of causative micro-organisms and antimicrobial susceptibilities.
Types of vascular access
Haemodialysis requires a reliable, repetitive access to the circulation, capable of providing rapid extracorporeal blood flow. Permanent vascular access should be easily accessible and suitable for undisturbed, long-term use. This is generally obtained by an a-v fistula, by a synthetic a-v fistula (a-v graft) composed of polytetrafluoroethylene (PTFE), or by a catheter, either for acute or for chronic use (double-lumen, cuffed tunnelled catheters)
Epidemiology of vascular access infection
Risk factors for septicaemia
Emerging resistance
Management of the infected vascular access (diagnosis, management) Diagnosis
Management
Antibiotic therapy
Catheter management
Salvage of the catheter
Catheter exchange
Catheter removal
Prevention of catheter infection
Practical guidelines
Notes
References
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