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Nephrol Dial Transplant (2000) 15: 307-311
© 2000 European Renal Association-European Dialysis and Transplant Association

Editorial Comments

Comparison of survival on CAPD and haemodialysis: statistical pitfalls

Wim Van Biesen1, Raymond Vanholder1, Dirk Debacquer2, Guy De Backer2 and Norbert Lameire1

1 Renal Division, Department of Internal Medicine and 2 Department of Social Medicine and Epidemiology, University Hospital Gent, Gent, Belgium

Correspondence and offprint requests to: N. Lameire, Department of Internal Medicine, Renal Division, University Hospital, De Pintelaan 185, B-9000 Gent, Belgium.

Introduction

Although the life expectancy of patients with end-stage renal disease (ESRD) has improved over the last decade, it is still below that of the general population.

Besides renal transplantation, an ESRD patient and his treating physician can basically choose between two different modalities: haemodialysis (HD) and peritoneal dialysis (PD). Since most centres can offer both PD and HD, the choice of an appropriate renal replacement therapy (RRT), both for the physician and for patient, is influenced by a number of medical and non-medical factors [1]. It is quite obvious that for the patients, total survival and quality of life are among the most decisive factors determining their decision. As many patients will change dialysis modality during their life-time, we believe that outcome of different consecutive RRT modalities is more important than that of one single modality. Besides patient survival, technique failure and its underlying causes and the outcome . . . [Full Text of this Article]

Statistical methods of survival analysis

Kaplan–Meier and Cox proportional hazards

Standardized mortality ratios and Poisson analysis

Incident vs prevalent patient inclusion

Clinical relevance

References


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