Nephrol Dial Transplant (2000) 15: 299-301
© 2000 European Renal Association-European Dialysis and Transplant Association
Editorial Comments
Cocaine use and kidney damage
V. Medical University Clinic, Klinikum Mannheim, Mannheim, Germany
Correspondence and offprint requests to: F. J. van der Woude, V. Medical University Clinic, Klinikum Mannheim, Theodor-Kutzer-Ufer 1–3, D-68135 Mannheim, Germany.
The high frequency of cocaine abuse has been well documented. In a university population in the US 6% of adolescents were cocaine users as documented by hair analysis [1], in Switzerland about 3% of adolescents had taken heroin or cocaine at least once in their life [2]. Apart from having mood elevating properties, cocaine is capable of causing myocardial infarction, arrythmia, sudden death, stroke, seizures, bowel necrosis, and numerous other complications [3]. The acute and chronic effects of cocaine use on other vasculatures than the kidney have been reasonably well known, the full extent of the effects of cocaine on the kidney, however, has become apparent more recently.
In the following, I discuss renal pathology induced
Cocaine and rhabdomyolysis
Cocaine and end-stage renal disease without rhabdomyolysis
Cocaine exposure in utero
Conclusion
References
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