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Nephrol Dial Transplant (2000) 15: 139-141
© 2000 European Renal Association-European Dialysis and Transplant Association

Editorial Comments

Functional genomics in nephrology

Masaru Takenaka and Enyu Imai

Division of Nephrology, Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Osaka, Japan

Correspondence and offprint requests to: Enyu Imai MD, Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine (A8), 2–2 Yamadaoka, Suita, Osaka, 565-0871 Japan.

Introduction

We are facing a new era in molecular biology. The complete DNA sequences of the genomes of many organisms have been analysed. The Human Genome Project is scheduled to finish prior to 2003. Now it is announced that approximately 90% of the data will be made accessible to the public in the coming year. This means that cloning of genes or characterization of the genomic structures will no longer be main issues in the near future. Expanding DNA databases such as GenBank are accumulating more than 3 million sequence records. Most of the data has come from EST (expressed sequence tag) projects collecting sequences directly from whole cDNA libraries that started in 1990s [1,2]. More than 1.2 million entries for . . . [Full Text of this Article]

`Functional genomics' to understand how differential genes work

Functional genomics in nephrology

Conclusions

References


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