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Nephrol Dial Transplant (1999) 14: 2291-2292
© 1999 European Renal Association-European Dialysis and Transplant Association

Editorial Comments

Hypertension and the risk of intracerebral haemorrhage: special considerations in patients with renal disease

Amanda G. Thrift1,3, Roger G. Evans2 and Geoffrey A. Donnan3

1 Department Epidemiology and Preventive Medicine, Monash Medical School, Alfred Hospital, Prahran, 2 Department of Physiology, Monash University, Clayton, and 3 National Stroke Research Institute, Austin and Repatriation Medical Centre, Heidelberg West, Victoria, Australia

Correspondence and offprint requests to: Dr A. Thrift, National Stroke Research Institute, Boronia Centre, Austin and Repatriation Medical Centre, Banksia Street, West Heidelberg, Victoria 3081, Australia.

Intracerebral haemorrhage (ICH) comprises about 10–15% of strokes and is associated with a high mortality rate and a high level of persistent disability in survivors [1,2]. Because there is little potential to ameliorate the damage after ICH has occurred, prevention is of particular importance.

There is now quite clear evidence that hypertension is the most powerful risk factor for ICH. In a recent case-control study that involved 331 cases of primary ICH and the same number of matched controls, the adjusted odds ratio (OR) for ICH among hypertensives was 2.45 (95% confidence interval (CI) 1.61–3.73) . . . [Full Text of this Article]

Ceasing antihypertensive medication use increases the risk of ICH

Implications for patients with renal disease

Greater risk of ICH among younger hypertensives

Conclusions

Acknowledgments

References


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