Skip Navigation



NDT Advance Access published online on July 8, 2009
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfp332
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by da Silva, G. V.
PubMed
Right arrow PubMed Citation
Right arrow Articles by da Silva, G. V.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Home blood pressure monitoring in blood pressure control among haemodialysis patients: an open randomized clinical trial

Giovanio Vieira da Silva1, Silvana de Barros1, Henry Abensur2, Katia Coelho Ortega1, Décio Mion, Jr1 Cochrane Renal Group Prospective Trial Register: CRG060800146

1 Nephrology Division, Hypertension Unit, University of São Paulo School of Medicine 2 Echocardiography Service of Hospital Beneficiência Portuguesa, São Paulo, Brazil

Correspondence and offprint requests to: Giovanio Vieira da Silva; E-mail: giovanio{at}usp.br



  Abstract

Background. It is not known if the adjustment of antihypertensive therapy based on home blood pressure monitoring (HBPM) can improve blood pressure (BP) control among haemodialysis patients.

Methods. This is an open randomized clinical trial. Hypertensive patients on haemodialysis were randomized to have the antihypertensive therapy adjusted based on predialysis BP measurements or HBPM. Before and after 6 months of follow-up, patients were submitted to ambulatory blood pressure monitoring (ABPM) for 24 h, HBPM during 1 week and echocardiogram.

Results. A total of 34 and 31 patients completed the study in the HBPM and predialysis BP groups, respectively. At the end of study, the systolic (SBP) and diastolic (DBP) blood pressure during the interdialytic period measured by ABPM were significantly lower in the HBPM group in relation to the predialysis BP group (mean 24-h BP: 135 ± 12 mmHg/76 ± 7 mmHg versus 147 ± 15 mmHg/79 ± 8 mmHg; P < 0.05). In the HBPM analysis, the HBPM group showed a significant reduction only in SBP compared to the predialysis BP group (weekly mean: 144 ± 21 mmHg versus 154 ± 22 mmHg; P < 0.05). There were no differences between the HBPM and predialysis BP groups in relation to the left ventricular mass index at the end of the study (108 ± 35 g/m2 versus 110 ± 33 g/m2; P > 0.05).

Conclusions. Decision making based on HBPM among haemodialysis patients has led to a better BP control during the interdialytic period in comparison with predialysis BP measurements. HBPM may be a useful adjuvant instrument for blood pressure control among haemodialysis patients.

Keywords: ambulatory blood pressure monitoring; haemodialysis; home blood pressure monitoring; hypertension

Received for publication: 1. 7.08
Accepted in revised form: 15. 6.09


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.