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NDT Advance Access published online on June 13, 2009
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfp293
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© The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Cryptococcal granulomatous interstitial nephritis and dissemination in a patient with untreated lupus nephritis

Vinoi George David1, Anila Korula2, Lisa Choudhrie2, Joy Sarojini Michael3, Shibu Jacob1, Chakko Korula Jacob1 and George T. John1

1 Department of Nephrology 2 Department of Pathology 3 Department of Microbiology, Christian Medical College, Tamil Nadu, Vellore 632004, India

Correspondence and offprint requests to: George T. John; E-mail: george{at}cmcvellore.ac.in



  Abstract

Infection is a significant cause of mortality and morbidity in systemic lupus erythematosus (SLE). There are many reports of cryptococcal infection in patients with SLE, on immunosuppression. However, untreated lupus with cryptococcal infection and dissemination is rare. CD4 lymphopaenia is not reported in such patients. We describe a patient with untreated SLE to be having cryptococcal granulomatous interstitial nephritis and dissemination with CD4 lymphopaenia.

Keywords: cryptococcus; dissemination; interstitial nephritis

Received for publication: 20. 1.09
Accepted in revised form: 26. 5.09


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