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NDT Advance Access published online on November 25, 2008
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfn649
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Cardiac tamponade in diarrhoea positive haemolytic uraemic syndrome

Javed Mohammed1, Guido Filler1,2, April Price1,3 and Ajay P. Sharma1,2

1 Department of Paediatrics 2 Division of Nephrology 3 Division of Critical Care Medicine, Children's Hospital at London Health Science Centre, University of Western Ontario, London, Ontario, Canada

Correspondence and offprint requests to: Guido Filler, Department of Paediatrics, Children's Hospital of Western Ontario, 800 Commissioners Road East, London, Ontario N6A 5W9, Canada. Tel: +1-519-685-8377; Fax: +1-519-685-8551; E-mail: guido.filler{at}lhsc.on.ca



  Abstract

The spectrum of extra-renal involvement secondary to diarrhoeal (D+) haemolytic uraemic syndrome (HUS) includes neurological, gastrointestinal, hepatic, pancreatic and cardiac complications. Among the cardiac complications, myocardial injury has been more commonly reported with HUS. Literature is scarce on HUS-associated pericardial involvement. We report a HUS-induced significant pericardial effusion that resulted in a cardiac tamponade. We also discuss the diagnostic and therapeutic implications of this complication.

Keywords: HUS; pericardial effusion; troponin-I

Received for publication: 9. 8.08
Accepted in revised form: 28.10.08


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